STANDARD COMPETENCIES:

 

 1. Illustrate compliance with all established OSHA safety standards

 2. Communicate using common clinical chemistry terminology relating basic chemical theories,

    clinical applications and disease correlations (where applicable) for:

      a. OSHA standards and safe practices in the clinical chemistry laboratory

      b. Basic chemistry instrumentation and immunoassay methodology

      c. Kidney, Liver and Thyroid functions

      d. Carbohydrate metabolism

      e. Biomarkers of cardiac damage and indicators of CVD

      f. NPN, hormones, lipids, proteins, iron, calcium, magnesium and phosphorus

      g. Acid-base balance and blood gasses

      h. Serum protein electrophoresis

      i. Therapeutic drug monitoring

      j. Toxicology

 3. Prepare, analyze and appraise quality control materials and calibrators for use in

    clinical chemistry procedures using dilutions, serial dilutions, percent and molarity solutions,

    if applicable, with 100% accuracy.

 4. Perform clinical chemical testing using a basic chemistry analyzer and measure analytes within

    2 standard deviations of known quantities.

 5. Identify reference ranges and critical values for all discussed chemistry tests and correctly evaluate

    patient test results in clinical situations using those reference ranges.

 6. Evaluate chemistry test results for technical errors or abnormalities and formulate reasons for such results.

 7. Interpret specific biochemical marker results with normal and abnormal human physiology as related to

    specific overall body organs, systems, functions and of patient situations in health and disease.

 8. Actively participate in small work groups and cooperative learning teams, where each student will demonstrate

    professional qualities and behavior of a laboratorian as outlined in the student program guide.

 TOPICAL OUTLINE:

 

 I. Quality assurance in the clinical chemistry laboratory – analytical variables

      a. Calibration verification

      b. Calibration and analyzing a standard curve

      c. Lot to lot variations

      d. Quality Control

      e. Establishing a reference range

      f. Interfering substances

      g. Maintenance and troubleshooting of chemistry instruments

      h. Teach other MLT students or designated individuals routine maintenance procedures

 II. Laboratory Math Review

      a. Serial dilutions

      b. V1C1

      c. QC statistics

 III. Instrumentation

      a. Spectrophotometry

      b. Immunoassay

      c. Electrophoresis

      d. Chromatography

 IV. Carbohydrates, hypoglycemia and hyperglycemia including diabetes biomarkers

 V. Kidney disorders and biomarkers

 VI. Liver disorders and biomarkers

 VII. Hepatitis biomarkers

 VIII. Proteins as biomarkers for disease and Protein Electrophoresis

 IX. Electrolytes (including Magnesium, Calcium, Phosphorus)

 X. Blood gasses and acid / base balance

 XI. Lipid testing and cardiac biomarkers

 XII. Therapeutic Drug Monitoring

 XIII. Trace Elements

 XIV. Endocrinology including thyroid studies